New 19-Oxygenated Steroids from the Soft Coral Nephthea chabrolii
نویسندگان
چکیده
In order to search for novel bioactive substances from marine organisms, we investigated the acetone extract of the soft coral Nephthea chabrolii collected at San-Hsian-Tai, Taitong County, Taiwan. From this extract three new 19-oxygenated steroids, nebrosteroids N-P (1-3) were isolated. The structures of these compounds were elucidated by extensive spectroscopic analyses.
منابع مشابه
New Steroids from the Soft Coral Nephthea chabrolii
A new cytotoxic 19-oxygenated steroid, nebrosteroid Q(1) and two new cytotoxic 19-norergosterols, nebrosteroids R and S (2 and 3) were isolated from the soft coral Nephthea chabrolii collected at San-Hsian-Tai. The structures of nebrosteroids Q-S (1-3) were elucidated by spectral analysis, and their cytotoxicity against selected cancer cells as well as antiviral activity against human cytomegal...
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This second part of the review dwells on Nephthea chabrolii and Nephthea Sp. which contain isoketochabrolic acid, ketochabrolic acid, sesquiterpenes, diterpenes and steroids. Corresponding biological activities such as anti-inflammatory and cytotoxic activities have also been observed for the isolated constituents. Most of the new compounds isolated from the genus Nephthea are from N. chabrolii...
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عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2012